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Announcements
Questions
Section 5.8: Irreversible Inhibition
Covalent Modification of Serine
Covalent Modification of Glutamate
Covalent Modification of Lysine
Acetylcholinesterase Inhibitors and Alzheimers
AChE Inhibitors
Section 5.9: Allosteric Enzymes
Properties of Allosteric Enzymes
Phosphofructokinase
Structure of Phosphofructokinase
Models of Allosteric Regulation
The Concerted Model
The Sequential Model
The Composite Model for Hemoglobin
Section 5.10: Enzyme Regulation
Phosphorylation
Section 5.11: Multi-Enzyme Complexes
References
Questions
Next Lecture: Sections 6.1 - 6.3